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[texts]Why do clinicians not refer patients to online decision support tools? Interviews with front line clinics in the NHS. (Volume 2) - Elwyn, Glyn
This article is from BMJ Open, volume 2.AbstractObjective: To assess whether clinical teams would direct patients to use web-based patient decision support interventions (DESIs) and whether patients would use them. Design: Retrospective semistructured interviews and web server log analysis. Participants and settings: 57 NHS professionals (nurses, doctors and others) in orthopaedic, antenatal, breast, urology clinics and in primary care practices across 22 NHS sites given access to DESIs hosted o...
Downloads: 1
[texts]Chlamydia and Gonorrhea Infections in HIV-positive Women in Urban Lusaka, Zambia. (Volume 4) - Alcaide, Maria L
This article is from Journal of Global Infectious Diseases, volume 4.AbstractBackground:: Sexually transmitted infections (STIs) remain an important public health issue in sub-Saharan Africa. STIs in HIV-positive women are associated not only with gynecological complications but with increased risk of HIV transmission to HIV-negative partners and newborns. Aims:: The aims of this study are to determine the prevalence of chlamydia (CT) and gonorrhea (GC) and examine the demographic characteristic...
Downloads: 1
[texts]Promoting male involvement to improve PMTCT uptake and reduce antenatal HIV infection: a cluster randomized controlled trial protocol. (Volume 11) - Peltzer, Karl
This article is from BMC Public Health, volume 11.AbstractBackground: Despite the availability of a dual therapy treatment protocol and infant feeding guidelines designed to prevent mother to child transmission (PMTCT) of HIV, of the over 1 million babies born in South Africa each year, only 70% of those born to HIV positive mothers receive dual therapy. Similar to other resource-poor nations facing the integration of PMTCT into routine pregnancy and infant care, efforts in South Africa to scale...
Downloads: 2
[texts]High pressures and asymmetrical stresses in the scoliotic disc in the absence of muscle loading. (Volume 2) - Meir, Adam R
This article is from Scoliosis, volume 2.AbstractBackground: Loads acting on scoliotic spines are thought to be asymmetric and involved in progression of the scoliotic deformity; abnormal loading patterns lead to changes in bone and disc cell activity and hence to vertebral body and disc wedging. At present however there are no direct measurements of intradiscal stresses or pressures in scoliotic spines...
[texts]HIV knowledge, disclosure and sexual risk among pregnant women and their partners in rural South Africa. (Volume 10) - Shikwane, Molatelo Elisa
This article is from Sahara J, volume 10.AbstractPartner involvement has been deemed fundamental for the prevention of mother-to-child transmission (PMTCT) of HIV, although it remains difficult to achieve. This study aimed to explore the attitudes and behaviours of pregnant women and their partners who participated in a behavioural risk reduction intervention in six community health centres in the Mpumalanga province of South Africa...
Downloads: 2
[texts]Integrating a family-focused approach into child obesity prevention: Rationale and design for the My Parenting SOS study randomized control trial. (Volume 11) - Ward, Dianne S
This article is from BMC Public Health, volume 11.AbstractBackground: More than 20% of US children ages 2-5 yrs are classified as overweight or obese. Parents greatly influence the behaviors their children adopt, including those which impact weight (e.g., diet and physical activity). Unfortunately, parents often fail to recognize the risk for excess weight gain in young children, and may not be motivated to modify behavior...
Downloads: 1
[texts]Risk factors for unplanned pregnancy among young women in Tanzania. (Volume 39) - Calvert, Clara
This article is from The Journal of Family Planning and Reproductive Health Care, volume 39.AbstractBackground: With effective contraceptives available, unplanned pregnancies are preventable and educational interventions have been cited as a promising platform to increase contraceptive use through improving knowledge. However, results from trials of educational interventions have been disappointing...
Downloads: 2
[texts]Iron Overload and Diabetes Risk: A Shift From Glucose to Fatty Acid Oxidation and Increased Hepatic Glucose Production in a Mouse Model of Hereditary Hemochromatosis. (Volume 60) - Huang, Jingyu
This article is from Diabetes, volume 60.AbstractOBJECTIVE: Excess tissue iron levels are a risk factor for diabetes, but the mechanisms underlying the association are incompletely understood. We previously published that mice and humans with a form of hereditary iron overload, hemochromatosis, exhibit loss of β-cell mass. This effect by itself is not sufficient, however, to fully explain the diabetes risk phenotype associated with all forms of iron overload...
Downloads: 5
[texts]HPTN 071 (PopART): Rationale and design of a cluster-randomised trial of the population impact of an HIV combination prevention intervention including universal testing and treatment - a study protocol for a cluster randomised trial. (Volume 15) - Hayes, Richard
This article is from Trials, volume 15.AbstractBackground: Effective interventions to reduce HIV incidence in sub-Saharan Africa are urgently needed. Mathematical modelling and the HIV Prevention Trials Network (HPTN) 052 trial results suggest that universal HIV testing combined with immediate antiretroviral treatment (ART) should substantially reduce incidence and may eliminate HIV as a public health problem...
Downloads: 2
[texts]Linking Women Who Test HIV-Positive in Pregnancy-Related Services to HIV Care and Treatment Services in Kenya: A Mixed Methods Prospective Cohort Study. (Volume 9) - Ferguson, Laura
This article is from PLoS ONE, volume 9.AbstractIntroduction: There has been insufficient attention to long-term care and treatment for pregnant women diagnosed with HIV. Objective and Methods: This prospective cohort study of 100 HIV-positive women recruited within pregnancy-related services in a district hospital in Kenya employed quantitative methods to assess attrition between women testing HIV-positive in pregnancy-related services and accessing long-term HIV care and treatment services...
Downloads: 2
[texts]Human Papillomavirus Vaccination in Tanzanian Schoolgirls: Cluster-Randomized Trial Comparing 2 Vaccine-Delivery Strategies. (Volume 206) - Watson-Jones, Deborah
This article is from The Journal of Infectious Diseases, volume 206.AbstractBackground.We compared vaccine coverage achieved by 2 different delivery strategies for the quadrivalent human papillomavirus (HPV) vaccine in Tanzanian schoolgirls.Methods.In a cluster-randomized trial of HPV vaccination conducted in Tanzania, 134 primary schools were randomly assigned to class-based (girls enrolled in primary school grade [class] 6) or age-based (girls born in 1998; 67 schools per arm) vaccine delivery...
Downloads: 4
[texts]High prevalence and incidence of human papillomavirus in a cohort of healthy young African female subjects. (Volume 89) - Watson-Jones, Deborah
This article is from Sexually Transmitted Infections, volume 89.AbstractObjectives: We measured the prevalence and incidence of human papillomavirus (HPV) infection in young female subjects recruited for a safety and immunogenicity trial of the bivalent HPV-16/18 vaccine in Tanzania. Methods: Healthy HIV negative female subjects aged 10–25 years were enrolled and randomised (2:1) to receive HPV-16/18 vaccine or placebo (Al(OH)3 control)...
Downloads: 3
[texts]Patterns of herpes simplex virus shedding over 1 month and the impact of acyclovir and HIV in HSV-2-seropositive women in Tanzania. (Volume 87) - Tanton, Clare
This article is from Sexually Transmitted Infections, volume 87.AbstractObjectives: Few studies have examined the frequency and duration of genital herpes simplex virus (HSV) shedding in sub-Saharan Africa. This study describes HSV shedding patterns among a sample of HSV-2-seropositive women enrolled in a placebo-controlled trial of HSV suppressive therapy (acyclovir 400 mg twice a day) in Tanzania...
Downloads: 2
[texts]Pregnancy and contraceptive use among women participating in an HIV prevention trial in Tanzania. (Volume 88) - Odutola, Aderonke
This article is from Sexually Transmitted Infections, volume 88.AbstractObjectives: Information on pregnancy rates and factors associated with pregnancy and contraceptive use is important for clinical trials in women in sub-Saharan Africa where withdrawal of investigational products may be required in the event of pregnancy with a consequent effect on sample size and trial power. Methods: A prospective cohort analysis of pregnancy and contraceptive use was conducted in Tanzanian women enrolled i...
Downloads: 3
[texts]Costs of delivering human papillomavirus vaccination to schoolgirls in Mwanza Region, Tanzania. (Volume 10) - Quentin, Wilm
This article is from BMC Medicine, volume 10.AbstractBackground: Cervical cancer is the leading cause of female cancer-related deaths in Tanzania. Vaccination against human papillomavirus (HPV) offers a new opportunity to control this disease. This study aimed to estimate the costs of a school-based HPV vaccination project in three districts in Mwanza Region (NCT ID: NCT01173900), Tanzania and to model incremental scaled-up costs of a regional vaccination program...
Downloads: 6
[texts]Prevalence of Human Papillomavirus in Adolescent Girls Before Reported Sexual Debut. (Volume 210) - Houlihan, Catherine F.
This article is from The Journal of Infectious Diseases, volume 210.AbstractBackground. Human papillomavirus (HPV) vaccines are recommended for girls prior to sexual debut because they are most effective if administered before girls acquire HPV. Little research has been done on HPV prevalence in girls who report not having passed sexual debut in high HPV-prevalence countries.Methods. Using attendance registers of randomly selected primary schools in the Mwanza region of Tanzania, we enrolled...
Downloads: 3
[texts]Safety and Immunogenicity of Human Papillomavirus-16/18 AS04-Adjuvanted Vaccine: A Randomized Trial in 10-25-Year-Old HIV-Seronegative African Girls and Young Women. (Volume 207) - Sow, Papa Salif
This article is from The Journal of Infectious Diseases, volume 207.AbstractBackground. Cervical cancer is a major public health problem for women in sub-Saharan Africa. Availability of a human papillomavirus (HPV) vaccine could have an important public health impact.Methods. In this phase IIIb, double-blind, randomized, placebo-controlled, multicenter trial (NCT00481767), healthy African girls and young women seronegative for human immunodeficiency virus (HIV) were stratified by age (10–1...
Downloads: 3
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